E-Pure Isomers with GG- Gold

$69.99 or Original price was: $69.99.Current price is: $62.99. / month

Benefits  

  1. Helps support brain health, cognition and memory 
  2. Supports antioxidant status 
  3. Supports normal neuron function and health 



In stock

Description

Unleashing the Power of E-Pure Isomers with GG-Gold: Your Key to Vibrant Aging

Meet E-Pure Isomers with GG-Gold, not just a supplement but a revolutionary elixir for those seeking vibrant aging and regeneration. Did you know that conventional Vitamin E might not be delivering the most potent and antioxidant-rich components? Let’s dive into the transformative world of E-Pure Isomers with GG-Gold, a true game-changer in the pursuit of healthy aging.

A Symphony of Vitality: Tocotrienols and Geranylgeraniol Unite:

E-Pure Isomers with GG-Gold is more than just a supplement; it’s a harmony of tocotrienols and geranylgeraniol, two formidable ingredients that dance together to support healthy aging, cellular energy generation, and the maintenance of muscle and bone mass during the aging process.

Unlocking the Power of Tocotrienols (T3): A Gift from Annatto:

Tocotrienols, the unsung heroes of the Vitamin E complex, bring a unique biochemical prowess not found in conventional tocopherol fractions. Derived from the richest known source, Annatto, E-Pure Isomers contains nearly 100% T3, offering unparalleled energy generation benefits. Beyond their positive influence on lipids, recent research hints at their potential to support robust, healthy bones.

Geranylgeraniol (GG): The Architect of Cellular Vitality:

GG, a crucial player in the cellular symphony, is indispensable for constructing cell membranes, generating energy in mitochondria, supporting hormone production (including testosterone), ensuring proper calcium trafficking, and even contributing to protein synthesis and modification. In the tapestry of aging, GG becomes a cornerstone, preventing the natural loss of muscle mass and bone density that can impact mobility, independence, and overall quality of life.

 

Benefits 

  1. Hormone synthesis
  2. Cardiovascular health and a healthy cholesterol profile.
  3. Skin, bone, and eye health.
  4. Healthy liver function.
  5. Insulin sensitivity and normal glycemic control.
  6. A healthy inflammatory response.
  7. Mitochondrial function and cellular energy

 

Ingredient highlights 

Geranylgeraniol: A Crucial Player in Cellular Dynamics:

Delving into the intricacies of cellular biology, geranylgeraniol takes center stage. This compound emerges not merely as an element but as a pivotal orchestrator in critical cellular processes. From steering protein synthesis to guiding cellular growth, differentiation, and survival, geranylgeraniol assumes a multifaceted role. Its involvement in the synthesis of CoQ10, heme A, dolichol, and prenylated proteins, along with its role in the conversion of Vitamin K1 to Vitamin K2, underscores its significance in cellular homeostasis.

Tailoring Unique Effects for Clinical Consideration:

In the clinical landscape, tocotrienols (T3) and geranylgeraniol offer unique therapeutic effects, particularly relevant to cardiovascular health. As the medical community grapples with the nuances of cholesterol management and the potential side effects associated with statin drugs, the enhanced degradation of HMG-CoA reductase by tocotrienols becomes a point of interest. Clinical trials showcasing substantial decreases in total cholesterol, LDL-C, triglycerides, C-reactive protein, and inflammatory cytokines associated with cardiovascular disease add depth to their clinical relevance.

Preserving Cellular Vitality: A Medical Approach to CoQ10 Synthesis:

The decline in CoQ10 synthesis, a phenomenon associated with aging or pharmacologically induced reduction, becomes a focal point in the medical narrative. Geranylgeraniol, intricately linked to the synthesis of CoQ10, unveils its potential role in mitigating the adverse effects associated with statin-induced myopathy and myotoxicity. The intricate interplay between geranylgeraniol and statins, with the former potentially offsetting undesirable effects without compromising cholesterol management, becomes a subject of clinical interest.

 

Support

*Cardiometabolic

*Bone Health

*Eye Health

*Cholesterol Management

 

Systems

Endocrine

Metabolism 

Cardiac

Bone

Eye

 

Recommended Use

Take 1 softgel  per day,  or as directed by your health‑care practitioner.

Ingredients

Vitamin E Isomers ( DeltaGold® delta and gamma tocotrienols), Trans-Geranylgeraniol (as GG-Gold™), medium chain triglycerides, softgel of bovine gelatin, glycerine, and purified water.

Ingredient Partners 

DeltaGold® is a registered trademark of American River Nutrition, LLC and protected by US Patent Numbers 6,350,453 and 8,586,109.
GG-Gold™ is a trademark of American River Nutrition, LLC and protected by US Patents No: 6,350,453, 7,989,006, and 8,293,290.

What to Avoid 

Warning: Consult with your health‑care practitioner if pregnant, breastfeed, or planning to become pregnant or taking any other prescription medications.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Research

1. Shidoji Y, Ogawa H. Natural occurrence of cancer-preventive geranylgeranoic acid in medicinal herbs. J Lipid Res. 2004 Jun;45(6):1092-103. DOI: 10.1194/jlr.M300502-JLR200.
2. Pearce, B.C., et al., Hypocholesterolemic activity of synthetic and natural tocotrienols. J Med Chem, 1992. 35(20): p. 3595-606.
3. Song, B.L. and R.A. DeBose-Boyd, Insig-dependent ubiquitination and degradation of 3-hydroxy-3-methylglutaryl coenzyme a reductase stimulated by delta- and gamma-tocotrienols. J Biol Chem, 2006. 281(35): p. 25054-61.
4. Qureshi, A.A., et al., Impact of delta-tocotrienol on inflammatory biomarkers and oxidative stress in hypercholesterolemic subjects. Clin. Exp. Cardiology, 2015. 6(4): p. 1000367.
5. Qureshi, A.A., et al., Dose-dependent modulation of lipid parameters, cytokines, and RNA by deltatocotrienol in hypercholesterolemic subjects restricted to AHA Step-1 diet. Brit J of Med & Med Res, 2015. 6(4): p. 351-366.
6. Sathasivam S. Statin induced myotoxicity. Eur J Intern Med. 2012 Jun;23(4):317-24. doi: 10.1016/j.
ejim.2012.01.004.
7. Tomaszewski M, Stępień KM, Tomaszewska J, Czuczwar SJ. Statin-induced myopathies. Pharmacol Rep. 2011;63(4):859-66.
8. Jaśkiewicz A, Pająk B, Litwiniuk A, Urbańska K, Orzechowski A. Geranylgeraniol Prevents Statin-Dependent Myotoxicity in C2C12 Muscle Cells through RAP1 GTPase Prenylation and Cytoprotective Autophagy. Oxid Med Cell Longev. 2018;2018:6463807. doi:10.1155/2018/6463807.
9. Cao P, Hanai J, Tanksale P, Imamura S, Sukhatme VP, Lecker SH. Statin-induced muscle damage and atrogin-1 induction is the result of a geranylgeranylation defect. FASEB J. 2009;23(9):2844–2854.
doi:10.1096/fj.08-128843.
10. Marcuzzi A, Piscianz E, Zweyer M, et al. Geranylgeraniol and Neurological Impairment: Involvement of Apoptosis and Mitochondrial Morphology. Int J Mol Sci. 2016;17(3):365. doi:10.3390/ ijms17030365.
11. Campia I, Lussiana C, Pescarmona G, Ghigo D, Bosia A, Riganti C. Geranylgeraniol prevents the cytotoxic effects of mevastatin in THP-1 cells, without decreasing the beneficial effects on cholesterol synthesis. Br J Pharmacol. 2009;158(7):1777–1786. doi:10.1111/j.1476-5381.2009.00465.x.

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